Gangnam
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Foret Seoul
Reverse Clinic Hongdae Branch
4.7(10+)
[ Reverse Clinic Network ]
Ellevie Rituo Cellrdiem effects,
what does an ECM skin booster fill into the skin?
✦ ECM refers to the environment that supports the skin
In Ellevie Rituo and Cellrdiem, “fill” means
supplementing the extracellular matrix components that support the skin.
Both products share the common feature of using acellular allograft dermis
processed by removing cells from human dermal tissue.
The skin is not made up of cells alone.
Collagen, elastin, and various components related to moisture
maintain the tissue’s structure and properties around the cells.
This framework that forms tissue outside the cells is the ECM.
Collagen is involved in the skin’s support, and elastin in its ability
to stretch and return. When looking at skin firmness, this is why
we examine not only the amount of each component, but also
the structure in which those components are arranged.
✦ How far does the explanation of “direct supplementation” go?
As we age, the skin undergoes changes including a decrease
and fragmentation of collagen fibers. These changes are linked not
only to the structure supporting the skin, but also to the environment
in which surrounding cells function.
What ECM-based approaches focus on is also this environment
around skin cells.
By supplying tissue components such as collagen obtained from donated dermis,
the goal is to complement the foundation that supports the skin.
However, the process of supplementing materials and the changes
they create in the skin should be understood separately.
Just because a component was once part of the skin does not mean
it will produce the same effect for every skin concern or remain permanently.
When you see the word “regeneration,” it helps to also look at what was
actually evaluated, such as skin texture, fine lines, and hydration status.
This is the process of connecting the principle behind the product with
results that can be visually confirmed.
✦ Even within the name skin booster, there are differences
When looking into skin boosters, it is easier to understand if you first
sort out what materials they use, rather than focusing on the product name.
Products using hyaluronic acid or polynucleotide (PN),
and products using acellular allograft dermis have different starting materials.
For example, hyaluronic acid has a water-attracting property and is used
in products that improve the skin’s moisture state.
Rejuran’s PN and Rituo·Cellrdiem’s acellular allograft dermis are not
the same ingredient referred to by different names.
That said, it is also hard to simply divide them by saying older products
are for moisture only, and ECM products are for regeneration only.
Evaluation items such as skin texture, fine lines, and firmness may overlap,
and each product differs in formulation, intended use, and accumulated evidence.
More important than a new name or generation classification is how well
it matches your current concerns and the goal of the procedure.
Just because you have tried another procedure before does not mean
you must switch to a new type this time.
✦ What should be compared between Rituo and Cellrdiem?
Rituo is a human tissue product whose ingredient is acellular allograft dermis,
and Cellrdiem is also a human tissue product, introduced as lyophilized
and finely ground powder made from homologous acellular dermis.
"Rituo and Cellrdiem have the same ingredients, but different particle sizes"
Both products are ECM-based skin boosters.
Rituo is known to be 100μm, while Cellrdiem is 75μm.
Because Rituo has relatively larger particles, it may act on enlarged pores
and overall sagging.
Cellrdiem has fine particles, which has the advantage of less resistance during injection,
and it may be helpful for people with thin skin or sensitivity to pain.
It can help improve fine skin texture and thin fine lines.
If you compare Rituo and Cellrdiem, the point of selection may differ depending on
skin type and the main concern (skin texture, condition, firmness, etc.),
but particle size alone cannot determine which is more effective.
✦ The 기준 for choosing starts with my own skin
Makeup that sits unevenly and more prominent fine lines,
and hollow cheeks or a sagging jawline may all feel broadly like
“loss of firmness,” but what needs to be checked is not the same.
Considering your skin condition, past procedure history, and the time
available for recovery can help narrow the options.
Rather than choosing by product name first, it is helpful to explain
specifically what problem you want to improve most right now.
When planning a procedure, along with the expected changes, you should
also consider discomfort after injection such as bruising, swelling, and pain.
This is because being described as a human-derived ingredient does not
eliminate the possibility of adverse reactions.
What ECM skin boosters aim to supplement is the foundation of the tissue
that makes up the skin. Once you understand this principle, it is important
to connect it to what changes you can expect for specific concerns such as
skin texture and fine lines.
When it becomes clear what is being filled and what you hope will change,
you can also continue with procedure selection and follow-up checks
using the same 기준.
✦ Final Q&A: Questions about ECM skin boosters
Even after understanding the principle, once you actually consider the procedure,
you may wonder about the recovery process, number of sessions, and how it relates
to other procedures. We have organized the information to know before choosing
into questions and answers.
■ Q. Which is better, Rituo or Cellrdiem?
A. It is difficult to rank them based only on the product name or particle size.
You should check the area you want to improve, your skin condition, and
the rationale for each product’s use together. First, have explained why
that product was chosen and what changes it is intended to target.
■ Q. Is it a procedure that makes the face look fuller like filler?
A. The goal of managing skin texture and fine lines, and the goal of filling
in facial hollows to change contours, should be distinguished.
Based on the explanation that ECM is being supplemented alone, you cannot
assume the same result as a typical volume filler, nor can you conclude that
there will be no volume change at all. Please first let us know the range
of change you want.
■ Q. If it looks good right after the procedure, does that mean it worked immediately?
A. The appearance right after treatment may include temporary swelling or
plumping from the injection. Rather than judging the final result based only on
the same day’s impression, it is better to check the progress at the time you were told.
When comparing skin texture or fine lines, it helps to keep the lighting, angle,
and facial expression similar.
■ Q. Is there little pain or embossing?
A. The degree of pain or how noticeable the injection area looks can vary
depending on the treatment area, method, and the individual.
It is difficult to conclude that there will be no pain or embossing just because
the particles are small. If you have an important schedule, it is best to let them know
in advance and check the expected swelling, bruising, and recovery process.
■ Q. Is one session enough? How many sessions are needed?
A. It is difficult to determine the number and interval that apply to everyone
based only on the product name. The initial skin condition, the goal, the product used,
and the progress after treatment must all be considered together.
If you are planning repeated sessions, check not only the number of treatments
but also at what point and by what 기준 you will evaluate the changes.
■ Q. Can it be done together with lifting procedures like Ulthera?
A. Whether they can be considered together and whether they can be performed on
the same day should be judged separately. This is because the plan may vary depending
on the device and product used, the treatment area, and the skin condition.
Tell the medical staff about recent and scheduled procedures, and decide together
the necessity, order, and interval.
■ Q. If the skin is sensitive, is it okay if it’s a human-derived ingredient?
A. Being human-derived alone does not mean it is suitable for every skin type
or that there is no risk of allergy or inflammation.
You should disclose any current skin disease or inflammation, past adverse reactions
after procedures, and any medications you are taking to confirm whether the procedure is possible.
After injection, redness, swelling, bruising, and pain may occur, and infection or
persistent nodules should also be watched for.
If pain or redness worsens, or if a lump persists, do not dismiss it as part of normal
recovery; contact the medical staff who performed the procedure and have it checked.
If you experience sudden severe pain, a change in skin color, or abnormal vision after
the procedure, do not wait and seek medical care immediately.
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